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Typically, infusions or injections can be given once or twice a week during the initial phase of therapy, in order to quickly increase glutathione levels in the body

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In certain embodiments, any controlled release otic formulation or composition described herein increases the exposure of a therapeutic agent and increases the Area Under the Curve (AUC) in otic fluids (e.g., endolymph and/or perilymph) by about 30%, about 40%, about 50%, about 60%, about 70%, about 80%, or about 90% compared to a formulation or composition that is not a controlled release otic formulation or composition

This is where the theoretical synergy comes into play, and its why this combination is a subject of such intense interest in advanced research circles

Abnormal liver phosphatidylcholine synthesis revealed in patients with acute respiratory distress syndrome