All supporting research is from preclinical animal studies and may not translate to humans
While CB-839 inhibited the proliferation of patient-derived glioma cell lines, it did not affect cell viability (103).In NSCLC, KEAP1 mutant NSCLC cell lines exhibit a dependence on Gln, and the GLS inhibitor CB-839 can inhibit Gln metabolism to exert anti-tumor effects (104)
The prevalence of neuropsychiatric symptoms in Alzheimers disease: Systematic review and meta-analysis
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