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Smokers with HIV are 61% more likely to develop any cancer

smokers in 2009: results from the International Tobacco Control (ITC) United States survey cohort

The three primary means of eliminating or reducing exposures involve the considerations of time, distance and shielding

If you can be more inclusive, your results may better generalize to the larger population, and thats the goal. By focusing on smokers who also drink heavily, this study not only showed that combination treatment could help the participants to quit smoking, it also showed that addressing smoking could have secondary effects on their drinking

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Both of these side effects were more common side effects in clinical trials, and were mild in most cases