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If you are deficient in vitamin B12, then the injections are very effective at raising your blood levels

It requires philanthropic, academic, or government-funded trials, which is a tractable problem rather than a sinister one

Long-term use of proton pump inhibitors and metformin can impair B12 absorption, necessitating monitoring or parenteral therapy

Vitamin B12 injections restore healthy vitamin B12 levels in people with a deficiency

For severe cases, the first dose is usually 1,000 mcg given intramuscularly every day or every other day for a week or two

Injections bypass the gut, and for these patients treatment is often a long-term maintenance strategy guided by their provider