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Concerning the regulation, CT2 seems to respond to progesterone stimuli ( Implications of CT2 in Cancer Unlike the restricted expression in healthy tissue, CT2 is largely expressed in several cancer types also originating from tissues that normally do not express this protein (Table 1)

Liver cells have the ability to convert an amino acid called methionine into cysteine, which is a precursor of glutathione

doi: 10.1016/j.cell.2007.10.036 333 StokesJ

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Aglycones pass through cell membranes to exert their biological functions via passive diffusion (Reference Aherne and OBrien20)