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33: 1460-1467 [DOI] [PubMed] [Google Scholar] 8).Kobayashi Y, Sakai C, Ishida T, Nagata M, Nakano Y, Ishida M: Mitochondrial DNA is a key driver in cigarette smoke extract-induced IL-6 expression

Increased nicotinic acetylcholine receptor protein underlies chronic nicotine-induced up-regulation of nicotinic agonist binding sites in mouse brain

Even though it is possible to calculate nicotine levels per puff, it's still challenging to measure how much nicotine is in a vape

Most current concerns come from the broader orthopedic and musculoskeletal literature, which suggests that EC exposure may not be biologically inert and may affect bone biology, wound healing, inflammation, and immune function

Historical Context: Originating in the United Kingdom, the tradition of No Smoking Day commenced on Ash Wednesday in 1984

Gilman & Xun 2004, pp