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Results of cellular thermal shift assay and molecular docking indicate that GPX4 is a potential direct target of carnosine, and carnosine shows promise as a potential inhibitor of ferroptosis for the treatment of renal I/R injury and other conditions associated with ferroptosis

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Obstructive sleep apnoea is independently associated with the metabolic syndrome but not insulin resistance state

This structural mismatch between BPC-157s biology and standard drug development pathways has contributed to the slow pace of clinical trial development, though it has not diminished scientific interest in the compound

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