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Hepatotoxicity caused by APAP overdose is one of the leading causes of acute liver failure (ALF) in the US and in some parts of Europe, limiting its clinical application

Similarly, Liebmann et al

PGC-1 inhibition reversed the beneficial effects of AMSCs in enhancing OXPHOS and mitochondria mass, as reflected by significantly diminished upregulation in OCR and mtDNA content induced by AMSCs in SR-18292-treated cells (Fig

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