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Glutathione supplement capsules contained 500mg of L-glutathione (fermentation) together with 250mg of ascorbic acid, 50mg of ALA, and 4mg (20mg) of zinc (as zinc aspartate) as additional ingredients, whereas the placebo capsules contained glucose powder in a gelatin coating

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In summary, efforts to uncover disease-modifying treatments in SCA3 should have a robust mechanistic background and, more importantly, sufficient preclinical data to support their reliability and efficacy prior to a potential clinical trial