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Gut microbiota dysbiosis caused by perfluorooctanoic acid can lead to fetal growth retardation through ferroptosis and inflammation [96]

These molecular alterations compromise sperm function, reducing their motility, fertilization capacity, and genetic integrity

For instance, GF mice have modified gut shape, characterized by diminished total intestinal mass, expanded cecum, shorter and thinner villi, and depleted mucus layers, decreased epithelial cell renewal, and impaired intestinal motility 12

Gap junctions are made up of six transmembrane proteins called connexins

In SH-SY5Y/MYCN cells, (M+D)/2 had no effect on cell death, while (M+D+V)/3 increased toxicity at 48 and 72 hours ( Figure 4A )

Calderon-Cabrera L, Duran-Galetta MG, Garcia I, Galetta D, Lacruz L, Naranjo R, Perez B, Ferreira E (2008) Determination of the N-acetylcysteine and methionine effects in the cerebellum of rats intoxicated with lead