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A significant advantage of surgical removal of the area includes the benefit of providing the entire specimen for histological analysis, with one study identifying foci of OSCC in 7% of excised oral leukoplakias

As a food additive, it has the E number E492

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Clin Transl Oncol (2017) 19(7):799825.10.1007/s12094-016-1607-9 19 ThunMJCarterBDFeskanichDFreedmanNDPrenticeRLopezADet al50-year trends in smoking-related mortality in the United States