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For tissue analysis, one testis from each animal was fixed in 10% neutral buffered formalin (NBF) for histopathological evaluation, while the contralateral testis was snap-frozen and stored at 80 C for Western blot analysis

There was no evidence of a positive effect of ALC on CIPN prevention in women undergoing breast cancer treatment

10.1093/toxsci/kfv136 Toxicol

Elevated Cu levels also deplete glutathione (GSH) and promote ROS generation, further contributing to cellular toxicity

As such, Adenylate Energy Charge (AEC) was particularly well maintained in supercooled RBCs in E-Sol5, reflecting their preserved glycolytic activity (Fig