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We summarize mechanistic insights across cellular and molecular domains, critically appraise preclinical and clinical findings, and discuss translational challenges that include bioavailability and brain penetration, study heterogeneity, biomarker guided stratification, and pediatric safety

Excessive AF is known to be associated with a reduction in the economic value of the carcass, as it does not contribute to commercial value

This could lead to enhanced feedback inhibition of growth hormone (GH) secretion and, consequently, reduced IGF-I secretion (21)

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How the immune system shapes atherosclerosis: roles of innate and adaptive immunity