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Unlike Semax, Selank can be redosed mid-day without disrupting sleep architecture, since it doesn't directly affect dopamine or norepinephrine

Stimulation with 6-hydroxydopamine (6-OHDA) markedly downregulates nuclear factor erythroid 2related factor 2 (NRF2) expression in PC-12 cells, elevates Fe 2+ and reactive oxygen species (ROS) levels, suppresses glutathione peroxidase 4 (GPX4), promotes both ferroptosis and apoptosis, inhibits cell proliferation, and causes neuronal damage

The coffee diterpene kahweol suppresses the cell proliferation by inducing cyclin D1 proteasomal degradation via ERK1/2, JNK and GKS3dependent threonine286 phosphorylation in human colorectal cancer cells

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PubMed PMID: 30727890