Comparison with pregabalin: A study in Canada among 44 people with nerve pain due to various conditions compared alpha-lipoic acid directly to pregabalin (Lyrica), a first-line prescription drug for neuropathic pain
Neurotox Res 37:669682 Shen J, Xie J, Ye L, Mao J, Sun S, Chen W, Wei S, Ruan S, Wang L, Hu H (2024) Neuroprotective effect of green tea extract (-)-epigallocatechin-3-gallate in a preformed fibril-induced mouse model of Parkinsons disease
Ceramide biosynthesis feeds into the production of sphingosine-1-phosphate (S1P), with the balance between ceramide and S1P levels acting as a determinant of apoptosis in oocytes (Morita et al, 2000)
Only two studies were found that showed an increase over normal limits
Magnusson KR, Hauck L, Jeffrey BM, Elias V, Humphrey A, Nath R, et al
Breyer, M