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Nevertheless, ongoing surveillance and research are important to fully characterize long-term safety as use of this therapy expands

Wait 30-60 minutes

Room temperature storage destroys them within 24 hours

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Because FOXO4-DRIs mechanism depends on disrupting the FOXO4p53 interaction, and because this interaction is only operative in cells with elevated FOXO4 expression, the compound preferentially targets the senescent cell population leaving FOXO4-low non-senescent cells largely unaffected

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