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Modeling indicates the pocket can accommodate -N-lactyllysine (slightly larger than acetyl and bearing an -hydroxyl) without major rearrangements [59, 63]

Moreover, under the catalysis of HO-1, heme could eventually be catabolized to bilirubin, which was confirmed to be an endogenous cytoprotective molecule because of its ability to scavenge peroxyl radicals (Calabrese et al

Chemotherapy drugs act on actively dividing cells, and as a result, the ovaries become natural targets for these drugs

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10.1002/hep.23335 46 TedeschiP

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