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[8] U.S

Nicotine and/or other toxic agents present in tobacco-based products may cause CH acting directly on the hypothalamus [12]

A recent critical appraisal published in the journal Tobacco Control by Sophie Braznell and colleagues in the UK of the known published interventional clinical trials of these products does not inspire confidence in recommending them: Of the 40 identified interventional clinical trials assessing heated tobacco products (HTP), 29 were industry affiliated and 11 were independent

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Studies have shown that smokers are more likely to develop cataracts