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Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies

miR-128, targets B-lymphoma Mo-MLV insertion region 1 (BMI1) which promotes cell proliferation and tumor growth and binds to the promoter region of PTEN thereby suppressing its expression (57)

Positively stained MT yielded a reddish brown-colored product in nuclei and cytoplasm of hepatocytes (A) control rat liver, (B) curcumin (400 mg/kg)-treated rat liver, (C) Cd (5 mg/kg)-treated rat liver, (D) curcumin (200 mg/kg) + Cd-treated rat liver, (E) curcumin (400 mg/kg) + Cd-treated rats liver, (F) vitamin C (100 mg/kg) + Cd-treated rat liver, (G) curcumin (200 mg/kg) + vitamin C + Cd-treated rat liver, (H) curcumin (400 mg/kg BW) + vitamin C + Cd-treated rat liver

Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study. BMC Gastroenterology

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