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The rates of adverse events in trials were similar to placebo groups

& Krenning, E

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[7] [8] Readers should check the current NICE Technology Appraisal for tirzepatide in weight management and the emc SmPC (medicines.org.uk) for the most up-to-date information on its licensed indications and eligibility criteria in the UK, as guidance may be updated

There is one small pilot study in humans (examining knee pain, where 7 of 12 participants reported sustained improvement beyond 6 months) and a 2025 safety study confirming BPC-157 was well tolerated in healthy adults

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