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In particular, the disruption of melatonin chronobiology due to alterations in the light-dark schedule can significantly affect tumor etiopathology, by altering cell proliferation, cell death, and nutrient supply 160

Cells were washed twice with ice-cold RPMI1640 medium with 10% FBS and incubated for 1 h at 4 C, with the indicated concentrations of dimer macrocycles or hHGF in RPMI1640 medium containing 10% FBS

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