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It is the primary subject of research for reversing connective tissue senescence, treating osteoarthritis, and functionalizing scaffolds for tissue engineering

10.1186/s13229-015-0010-7 [DOI] [PMC free article] [PubMed] [Google Scholar] 33.Politi P, Cena H, Comelli M, Marrone G, Allegri CE, Emanuele E, et al

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Obesity is a major public health problem that contributes both directly and indirectly to cardiovascular disease (CVD) and mortality