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Mice were initially trained to remain on the rotarod for a minimum of 5 min at a constant rotation speed of 5 rpm/min

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SmTGR Y296A was mixed with a range of NADPH concentrations and the reaction was monitored at 455 and 540 nm (Figures 7A,B)

2.3 Plants metabolic response to pesticides Plant secondary metabolites play a critical role in modulating pesticide absorption, translocation, and detoxification by enhancing enzymatic breakdown, facilitating conjugation, altering transport processes, and interacting with plant microbiomes