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Disturbed consciousness is a feature specific to BBE and differentiates this disease from FS

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Whilst compensatory mechanisms have evolved to defend against short-term perturbations of the methionine cycle (the choline/Betaine pathway and the folate cycle work together to provide methyl groups for the re-methylation of homocysteine to methionine) they can do so only if the biological mechanisms are able to draw on necessary enzymatic cofactors and raw ingredients provided from the diet

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CrossRef Advances in Continuous Glucose Monitoring and Integrated Devices for Management of Diabetes with Insulin-Based Therapy: Improvement in Glycemic Control Jee Hee Yoo, Jae Hyeon Kim Diabetes & Metabolism Journal.2023