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These demonstrated short-term safety in adults with normal renal and hepatic function

Now there are some reasons why b12 alone can help with metabolism but they are more subtle and likely only going to work if you have an actual deficiency

Mohammadi E, Qujeq D, Taheri H, Hajian-Tilaki K (2017) Evaluation of serum trace element levels and superoxide dismutase activity in patients with inflammatory bowel disease: Translating basic research into clinical application

To that end, his group has been testing a dietary supplement derived from whey protein called Immunocal

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