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Moosa A, Shu H, Sarachana T, Hu VW (2018) Are endocrine disrupting compounds environmental risk factors for autism spectrum disorder
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Sensory Symptoms Numbness, tingling, or pins and needles (paresthesia) typically distal/stocking-glove in polyneuropathy Burning pain, allodynia, hyperalgesia common in small-fiber predominant neuropathy and CIDP Loss of proprioception and vibration sense sensory ataxia, positive Romberg sign Loss of pain/temperature sensation (small fiber) risk of unnoticed wounds Motor Symptoms Distal muscle weakness (foot drop in peroneal neuropathy, wrist drop in radial neuropathy) Atrophy of intrinsic hand muscles (ulnar/median neuropathy) Hyporeflexia or areflexia (ankle jerks lost early in length-dependent polyneuropathy) Fasciculations in severe axonal loss Autonomic Symptoms Orthostatic hypotension, dizziness on standing Gastroparesis, constipation or diarrhea, nausea Neurogenic bladder (hesitancy, retention, incontinence) Anhidrosis or gustatory sweating Sexual dysfunction

Unlike testosterone-based approaches, PT-141 acts centrally on melanocortin receptors (MC3R, MC4R) in the brain, influencing desire through dopaminergic pathways rather than peripheral blood flow
Lean Muscle Gain As growth hormone and IGF-1 increase, patients often notice a boost in muscle protein synthesis , making it easier to gain lean muscle and recover from strength training