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These findings suggest a functional role for TGH in the mature fat cell, and indeed, Soni and colleagues (116) have identified TGH as an adipocyte lipase using functional proteomics

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7 Over 55% of the weighting in this meta-analysis was contributed by the LOOK AHEAD trial, which assessed whether intensive lifestyle interventions for weight loss would reduce cardiovascular morbidity and mortality in individuals with overweight or obesity and type 2 diabetes (T2DM)