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These electron-electron repulsions affect the Coordination number: When a ligand donates its electrons to a metal center to form a new metal-ligand bond, the electron density around the metal increases, raising the overall energy of the other M-L bonding electrons

every row is unpacked, with citations, in the sections that follow

Additionally, the enhancement of serine synthesis pathway in NRF2-addicted cancer cells (DeNicola et al

F.et al (2022)

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If you are looking for more context on safety, our glutathione safety guide is worth a look