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Taken together, metabolomic studies of long COVID, ME/CFS, and MDD show considerable similarities in the overall metabolic profiles associated with a disruption of energy production and an imbalance of potentially neuroprotective and detrimental metabolites, i.e., a deficiency of neuroprotective metabolites such as acetylcarnitine

Mean SD of at least 3 independent experiments

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PLoS ONE 9:e114923 Ricote M, Huang JT, Welch JS, Glass CK (1999) The peroxisome proliferator-activated receptor (PPAR) as a regulator of monocyte/macrophage function

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