and patients with pernicious anemia who have optic neuropathy COBALAMIN (Vitamin B12) Deficiency Causes Vegetarians (dietary deficiency) Older adults: atrophic gastritis affects 10% 30% and leads to decrease in hydrochloric acid secretion in the stomach and decreased absorption of Vitamin B12 The liver can store up to six years worth of Vitamin B12 so deficiencies are rare Effects of deficiency Megaloblastic anaemia (pernicious anaemia) Progressive demyelination of nerve cells Elevation in levels of circulating homocysteine that leads to production of defective collagen and elastin with a negative impact on arteries, bone and skin Deep vein thrombosis is associated with homocysteinemia that causes the activation of the intrinsic coagulation cascade Symptoms include fatigue, weakness, constipation, loss of appetite and weight loss Numbness, tingling of the feet imbalance, depression, confusion, dementia, poor memory and glossitis
Brain fog Poor concentration Irritability Mild cognitive decline Regular B12 injections may help improve clarity, focus and mood, especially in people with low or borderline levels
For any per-user calculation, use the dosage calculator rather than adjusting numbers by hand
Please visit a health care provider for evaluation, diagnosis and treatment of any symptoms you may be experiencing
Experience: Hike through high-Andean lake landscapes
Clinical evidence strength: AOD 9604 is weak, having failed six trials
