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In addition, L-2-HG accumulation in an acidic pH environment has been reported to result in HIF-1 stabilization in normoxia 91 (Fig

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The hydrogel provides a suitable microenvironment for the valence cycle of metal nanozymes, breaks the limitation of single-turnover catalysis, continuously drives the redox cycle, and sustains the catalytic activity of nanozymes in the long term

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