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36 CivilettoG.VaranitaT.CeruttiR.GorlettaT.BarbaroS.MarchetS.et al (2015)

ROS accumulation is positively correlated with pancreatic fibrosis in both acinar and islet tissues, confirming the role of OxS in fibrosis onset [36]

We used the 3xTg mouse model of AD, which expresses familial human isoforms of APP (APPSwe), Tau(tauP301L), and Presenilin (PS1M146V), and exhibits both A and tau pathology as well as cognitive deficits 13