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Lancet 2016;388:202338

Notably, increased expression of the transcription factor MYC, which is strongly associated with glutamine metabolism, induces the expression of several key enzymes in nucleotide biosynthesis, including phosphoribosyl pyrophosphate amidotransferase (PPAT) 36

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[Google Scholar] Mikus D., Sikiric P., Seiwerth S., Petricevic A., Aralica G., Druzijancic N., et al

(Baltimore Md) 43 (4), 817825