The adverse circumstances frequently encountered in solid tumor microenvironments encompassing low oxygen tension and, in many cases, mtDNA mutations or other bioenergetic impairments lead to severe decreases in OXPHOS 231,232
These molecules are crucial for both cancer and immune cells to meet biosynthetic and energy demands
In addition, ongoing research implicates diseases such as obesity, heart disease, and diabetes
Common mild effects: Temporary flushing or warmth at infusion site (typically brief) Mild headache in some patients at higher doses Rare nausea Important clinical considerations: Patients with asthma should be evaluated prior to IV glutathione because inhaled glutathione has been associated with bronchospasm in some asthmatic individuals
Holy basil (Ocimum tenuiflorum) 125 mg of a standardized extract twice daily (Lopresti 2022) Supplementation associated with improvements in Perceived Stress Scale and Profile of Mood States, Athens Insomnia Scale scores
Depletion of fossil fuels and anthropogenic climate changeA review
