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10.1016/j.jdcr.2019.03.011 239

In pharmacokinetic theory, a compound reaches approximately 97% of its steady-state plasma concentration after five consecutive half-life periods

Bioavailability is the measure of how much of a nutrient actually enters your bloodstream so your body can use it

doi: 10.3390/ijms21197318

Antinociceptive and Analgesic Effects DSIP demonstrated a potent antinociceptive effect when administered intracerebroventricularly or intracisternally in rodent models establishing central analgesic activity independent of peripheral opioid mechanisms

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