Animal model research demonstrated that depleting GSH via inhibition of GCL triggered a cascade of lipid peroxidation and cell death in mesencephalic cultures, identifying oxidative stress from glutathione insufficiency as a likely initiating mechanism in neurodegeneration
senescent cells and macrophages
Extracellular redox state: refining the definition of oxidative stress in aging
PCR fragments were purified with the QIAquick PCR purification kit from Qiagen
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