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doi: 10.1084/jem.20120833 77 Garcia-ManteigaJMMariSGodejohannMSpraulMNapoliCCenciSet al
Omega-3 fatty acids have also drawn a lot of interest because of their capacity to improve lipid profiles and reduce hepatic triglyceride levels, especially eicosapentaenoic acid and docosahexaenoic acid[184]
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Three interconnected pathways function as core suppressors of ferroptosis: (1) the GPX4-GSH system (central suppressor), (2) the SLC7A11-cystine import pathway (GSH synthesis), and (3) the AIF family member 2 (AIFM2, also known as FSP1)-NAD(P)Hquinone pathway (parallel protection) 84-87
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Mice, subcutaneous LD50: 9 mg/kg, lacrimation, convulsions or epilepsy, changes in the structure or function of salivary glands in the gastrointestinal tract
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