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According to the reports, coffee enema was effective for relieving constipation as caffeine increased the intestinal motility when absorbed in the intestinal mucosa, [21] and decreasing lipids and cholesterol as well as improving thyroid function

He, L., Feng, D., Guo, H., Zhou, Y., Li, Z., Zhang, K., et al

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Zou, S., Shimizu, T., Shimizu, S., Higashi, Y., Nakamura, K., Ono, H