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Acknowledgements The authors are indebted to Dr

There is a preferential transport of GSSG from the cytosol to the endoplasmic reticulum to maintain an adequate environment for protein disulfide bond formation and protein folding ( Glutathione and the -glutamyl cycle The synthesis, transport and catabolism of GSH occur in a series of enzymatic steps and transports of membrane that are collectively called -glutamyl cycle (Figure 5) ( - glutamyl cycle was postulated by Meister (Figure 5)

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Fish and meat are the richest sources of dietary UQ (Pravst et al., 2010)

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Generally, two types of enzymes are commonly employed in drug delivery via enzyme-responsive nanomaterial i.e