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Aging, cellular senescence, and mitochondrial dysfunction
Among these, polyphenols are widely studied for their broad biological activities, including the modulation of oxidative stress and inflammation
They should also be informed of the appropriate athletics department procedures for disseminating updates to the list
For example, excessive doses of the copper ionophore elesclomol can flood cells with copper, overwhelming antioxidant defenses and triggering lethal oxidative stress [247] whereas excessive copper supplementation can cause overload and ROS-mediated damage [248]
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