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Although blood-based tau biomarkers have demonstrated high diagnostic performance, additional accessible biofluids may provide alternative molecular information and further support screening and disease monitoring strategies

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For example, Lactiplantibacillus plantarum reduces the DNA-binding capacity of NF-B, thereby limiting the transcription of pro-inflammatory genes (258), whereas Lactobacillus brevis inhibits the phosphorylation of upstream kinases such as IRAK1 and AKT (259)

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