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BVC can significantly inhibit IL-6, IL-17A, and TNF- to reduce cartilage erosion and improve synovial tissue (6163)

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Therefore, future research must prioritize large-scale, long-term (2 years) RCTs employing standardized EPA/DHA formulations and doses targeted to achieve specific tissue or plasma levels

A specific feature of GPx8 is the presence of both a conserved N-terminal transmembrane domain and a C-terminal motif designed for the localization of the endoplasmic reticulum

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