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It was suggested that the differentiated production of IL-1 and IL-8 may be linked to the type of product applied, either an irritant or a sensitizer 39,40

108,187 Furthermore, the deletion of ZIP7 greatly enhances the ER stress response of proliferating progenitor cells, leading to apoptosis and disrupting intestinal epithelial cell proliferation and dryness

doi: 10.1007/s11739-016-1583-7 19 HigginsJPAltmanDGGtzschePCJniPMoherDOxmanADet al

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Aggresome formation is therefore recognized as a cytoprotective response serving to sequester potentially toxic misfolded proteins and facilitate their clearance by autophagy

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