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albicans has developed a safe mechanism for iron uptake and utilization whereby it absorbs iron using several different strategies, such as acquiring RBC-derived iron and inducing the expression of high-affinity iron permease gene CaFTR1 and ferrichrome-type siderophores [31,32,33,34]

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Furthermore, a legitimate AOD 9604 protocol involves baseline labs, a titration plan, and clinical follow-ups

The use of miRNAs to modulate the expression of the mutant A1AT gene and reduce the associated toxic effects has also been explored

However, brain distribution of A is variable among different diseases 28