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That lower pH is necessary for certain research compounds that simply won't dissolve at neutral pH
That combination gastric origin, enzymatic stability, and remarkable tissue breadth is what has driven decades of continuous preclinical research interest in this unique compound
A well-known risk factor in humans is hypercholesterolemia, i.e., elevated total cholesterol (TC) and low-density lipoprotein cholesterol (LDL) (Pourrajab et al., 2021), and other important contributors to this disease include inflammation, oxidative stress and insulin resistance (Subramani et al., 2017)
Since DmGSTS1-1 was highly expressed in the flight muscle, the localization of the corresponding GST enzyme might provide a protective role against oxidative stress generated from mitochondrial respiration [128]