Therefore, it will be interesting to determine how and to what extent the LDHB-mediated pro- and anti-ferroptotic functions associated with the lysosomes, peroxisomes, plasma membrane/cytoplasm, and mitochondria contribute to the total cellular ferroptotic activity
Tsai YL, Tseng YC, Chen YM, Wen TC, Jan JS
Helps regulate immunity, mood, and the neuromuscular system
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It also protects these cells from oxidative stress and slows cell death (apoptosis)
Acknowledgements We acknowledge the use of cryo-EM facilities at the Advanced Center for Electron Microscopy, Shanghai Institute of Materia Medica, Chinese Academy of Sciences