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Furthermore, ROS accumulation over time leads to irreversible damage, and Harman's (84) theory provides further insight into the role of extracellular ROS in triggering age-related cancer progression (85)
ROS are unstable oxygen-containing molecules that easily react with other molecules in a cell [14] and are generated after physiological dysfunctions or exposure to physical agents, such as ultraviolet rays and heat, chemical factors, environmental toxicants, smoking, alcohol, or even other factors, such as obesity, varicocele, aging, or diabetes [11]
Marotta V, Guerra A, Zatelli MC, Uberti ED, Di Stasi V, Faggiano A, Colao A, Vitale M
Mantiene una composicin de grasa corporal propicia, lo que favorece la sensibilidad a la insulina y regula los niveles de azcar
10.1038/s41598-017-18877-8 390 SavignacH