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Here's more about the importance of the gut-thyroid connection

Tsukuda, Journal of the American Chemical Society 127, (2005) 52615270

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Nonetheless, when a cell (e.g., a hepatocyte) is exposed to inflammation or oxidative stress, NRF-2 has the capacity to escape from regulation by KEAP1 through the increase in the transcription of mRNA from NRF-2, with the objective of depleting the reserves of KEAP1, which cannot be recycled because of the suppression of another NRF-2 [21]

Front Nutr (2022) 9:870162

Glutathione is a tripeptide molecule produced naturally in the liver and found in nearly every cell of the human body