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Seo EJ, Lee HR, Hwang SY, Oh DK, Kwon YU, Kchl K, Nestl B, Park JB, Bornscheuer UT (2025) Substrate-binding cavity engineering of the lipoxygenase from Pseudomonas aeruginosa to produce 8S- and 11S-hydroxyeicosatetraenoic acids

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Specifically, the increased loss of RBCs leads to the increased formation of bilirubin, which further triggers eryptosis by enhancing both Ca 2+ influx, SMase activation, and ceramide production, thus creating a vicious cycle

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(6) All authors have been personally and actively involved in substantial work leading to the paper, and will take public responsibility for its content

Description IGF-1 LR3 is built for extended activity and stability