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This V d ( 0.7) 23 For these drugs, the intrinsic clearance (CL int ) is very high, meaning the liver's metabolic capacity is so great that it can remove the drug much faster than it is delivered

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Glechongsides F-1 showed weak cytotoxicity effects against cancer cell lines A2780, Be1, A549, BGC-823, and HCT-8 with IC 50 values ranging from 3.77 to 30.95 M [58]